全文阅读
二仙合剂可治疗妇女高血压,在腎型高血压狗也有降压效果。本文用5种高血压大白鼠(神經型、腎型、腎上腺燙伤型、睾丸切除型及卵巢切除型)来比較降压作用,并观察性周期、前庭时值及某些加压物质的升压反应。每天灌胃二仙合剂10克/公斤,共2周,神經型、腎型及睾丸切除型的降压面积％分别为-9,-11及-15％,与同型对照組比較,降压“显著”,腎上腺燙伤型及卵巢切除型的降压“不显著”。每天灌服二仙合剂10克/公斤,共7周,对未成熟大白鼠生长及性腺发育无影响。对神經型、腎型及腎上腺燙伤型雌鼠的性周期紊乱亦无糾正作用。二仙合剂能延长腎型高血压鼠的前庭时值,但在其他型则变化不显著。无明显对抗去甲腎上腺素及垂体后叶素的加压反应的作用。
Erxian mixture can treat women’s hypertension, hypertension in dogs with antihypertensive effect. In this paper, five kinds of hypertensive rats (neurological, renal, adrenal scalded, orchidectomy and ovariectomy type) to compare the antihypertensive effect, and observe the sexual cycle, vestibular time and the rise of certain pressurized substances Pressure reaction. Administration of Erxian mixture daily 10 g / kg for 2 weeks, neurogenic, renal and orchidectomized type of antihypertensive area% -9, -11 and -15%, respectively, compared with the same type of control group, Significant “, adrenal scalded and ovariectomized type of antihypertensive” is not significant. " Ershu mixture daily dose of 10 g / kg, a total of 7 weeks, immature rat growth and gonadal development had no effect. Neuro-type, renal and adrenal scalded female sex disorder also no role in correcting. Erxian mixture can prolong the vestibular time of renal hypertensive rats, but the other types of changes were not significant. No significant antagonism of norepinephrine and pituitrin pressure response.